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CD200R Rat anti-Mouse, Alexa Fluor 647, Clone: OX-110 (also known as OX110), BD

Catalog No. BDB566345 Shop All BD Biosciences Products
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BDB566345 50 μg
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Catalog No. BDB566345 Supplier BD Biosciences Supplier No. 566345
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Description

Rat Monoclonal Antibody

The OX-110 monoclonal antibody specifically binds to CD200R which is also known as OX2 receptor 1 (Ox2r) or MOX2 receptor (Mox2r). CD200R is a type I transmembrane glycoprotein that is encoded by Cd200r1 (CD200 receptor 1) and belongs to the C2-set domain containing gene family within the Ig superfamily. CD200R is expressed by hematopoietic cells including monocytes, granulocytes, and T cells. CD200R functions as an inhibitory receptor when bound by its ligand, CD200. CD200R signaling can inhibit leucocyte functions such as the production of cytokines.

Alexa Fluor™ 647 conjugates are highly photostable and remain fluorescent over a broad pH range. The excitation and emission maxima are nearly identical to those of APC. However, APC tends to be brighter while Alexa Fluor™ 647 is more optimal for intracellular applications. This fluorochrome exhibits uncommon photostability, making it an ideal choice for use in fluorescence microscopy. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor™ 647 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD200R
Classification Monoclonal
Clone OX-110 (also known as OX110)
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Cd200r1, CD200 receptor 1, Orexin receptor 2, Ox2r, Mox2r, MO2R1
Host Species Rat
Immunogen Mouse CD200R Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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