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Invitrogen™ CD205 Monoclonal Antibody (IL-A114), PE
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Catalog No. PIMA528316
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100 Tests
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PIMA528316 100 Tests
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Catalog No. PIMA528316 Supplier Invitrogen™ Supplier No. MA528316
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Description

Mouse Monoclonal Antibody

Mouse anti Bovine CD205 antibody, clone IL-A114 recognizes bovine CD205 (also known as DEC205) and originally described as BoWC6. Reconstitute by adding 1 mL distilled water.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
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Specifications

Antigen CD205
Applications Flow Cytometry
Classification Monoclonal
Clone IL-A114
Concentration 1 mg/mL
Conjugate PE
Formulation PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene LY75
Gene Accession No. 0
Gene Alias CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Gene Symbols LY75
Host Species Mouse
Purification Method Protein G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 407236
Target Species Bovine
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Lyophilized
Isotype IgG1
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