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CD205 Monoclonal Antibody (PN-15), Invitrogen™

Catalog No. PIMA513365
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500 μL
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PIMA513365 500 μL
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Catalog No. PIMA513365 Supplier Thermo Scientific Supplier No. MA513365
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Description

Mouse Monoclonal Antibody

MA5-13365 targets Renal Cell Carcinoma Marker in IHC (P) and WB applications and shows reactivity with Human and Rat samples. The MA5-13365 immunogen is microsomal fraction of human renal cortical tissue homogenate.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD205
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone PN-15
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene LY75
Gene Accession No. O60449
Gene Alias CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Gene Symbols LY75
Host Species Mouse
Immunogen Microsomal fraction of human renal cortical tissue homogenate
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4065
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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