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Invitrogen™ CD205 Polyclonal Antibody
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Catalog No. PIPA583951
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100 μL
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PIPA583951 100 μL
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Catalog No. PIPA583951 Supplier Invitrogen™ Supplier No. PA583951
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRWTAYEKIN KWTDNRELTY SNFHPLLVSG RLRIPENFFE EESRYHCALI LNLQKSPFTG TWNFTSCSER HFVSLCQKYS EVKSRQTLQN ASETVKYLNN Highest antigen sequence indentity to the following orthologs: Mouse - 77%, Rat - 76%.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD205
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LY75
Gene Accession No. O60449
Gene Alias CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Gene Symbols LY75
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LY75. Recombinant protein control fragment (Product #RP-101107).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4065
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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