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CD206 Mouse, anti-Human, R718, Clone: 19.2, BD OptiBuild™

Catalog No. BDB751998 Shop All BD Biosciences Products
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BDB751998 50 μg
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Catalog No. BDB751998 Supplier BD Biosciences Supplier No. 751998
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Description

Mouse Monoclonal Antibody

The 19.2 monoclonal antibody specifically binds to CD206 which is also known as the macrophage mannose receptor (MMR) or C-type lectin domain family 13 member D (CLEC13D). CD206 is a type I transmembrane glycoprotein of approximately 162 kDa which binds to glycoconjugates containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the macrophage to bind to microorganisms through the MMR and internalize them during the process of phagocytosis. CD206 is expressed on human macrophages, endothelial cells, and cultured dendritic cells. It is not detected on resting monocytes. Mannose receptor expression is upregulated on peripheral blood mononuclear cells following 3 day incubation with GM-CSF.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD206
Applications Flow Cytometry
Classification Monoclonal
Clone 19.2
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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