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  6. Invitrogen™ CD207 (Langerin) Recombinant Rat Monoclonal Antibody (eBioRMUL.2) 

Invitrogen™ CD207 (Langerin) Recombinant Rat Monoclonal Antibody (eBioRMUL.2)

Catalog No. 740124T
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74-012-4T 100 μL
74-012-4TXS 20 μL
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Catalog No. 74-012-4T Supplier Invitrogen™ Supplier No. 740124T
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Description

Rat Recombinant Monoclonal Antibody

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD207 (Langerin)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone eBioRMUL.2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CD207
Gene Accession No. Q9UJ71
Gene Alias CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Gene Symbols CD207
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50489
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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