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Epredia™ Lab Vision™ CD22 Ab-4, Mouse Monoclonal Antibody

Catalog No. MS1087R1 Shop All Epredia Products
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MS1087R1 1 mL
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Description

Obtain accurate and reproducible results in immunohistochemistry experiments with Epredia™ CD22 Ab-4, Mouse Monoclonal Antibody.

CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types.In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells. CD22 is found highly expressed in follicular mantle and marginal zone B-cells, while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Host Species: Mouse

Clone: FPC1

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Epitope: Extracellular

Immunogen: Recombinant protein encoding the external domain of human CD22

Molecular Weight: 130-140kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)

Specifications

Antigen CD22 Ab-4
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone FPC1
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant Protein encoding the external domain of human CD22
Quantity 1 mL
Regulatory Status IVD
Research Discipline B-Cell
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG1
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