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CD22 Mouse, anti-Human, R718, Clone: HIB22, BD OptiBuild™

Catalog No. BDB752263 Shop All BD Biosciences Products
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BDB752263 50 μg
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Catalog No. BDB752263 Supplier BD Biosciences Supplier No. 752263
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Description

Mouse Monoclonal Antibody

The HIB22 monoclonal antibody specifically binds to CD22. CD22 is a 130-140 kDa glycosylated type I integral membrane protein present on the surface of mature B cells. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD22
Applications Flow Cytometry
Classification Monoclonal
Clone HIB22
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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