Invitrogen™ CD229 Monoclonal Antibody (312830)

Catalog No.	Quantity
PIMA524034	100 μg

Catalog No. PIMA524034 Supplier Invitrogen™ Supplier No. MA524034

Description

Rat Monoclonal Antibody

In Western blots, no cross-reactivity with recombinant human CD229 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

Specifications

• Antigen: CD229
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 312830
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: Ly9
• Gene Accession No.: Q01965
• Gene Alias: AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9
• Gene Symbols: Ly9
• Host Species: Rat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CD229/SLAMF3 Lys48-Phe454.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17085
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a