Invitrogen™ CD229 Monoclonal Antibody (HLy9.25)

Catalog No.	Quantity
PIMA110149	100 μg

Catalog No. PIMA110149 Supplier Invitrogen™ Supplier No. MA110149

Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

Specifications

• Antigen: CD229
• Applications: Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: HLy9.25
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene: Ly9
• Gene Accession No.: Q9HBG7
• Gene Alias: AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9
• Gene Symbols: Ly9
• Host Species: Mouse
• Immunogen: CD299-transfected 300.19 pre-B cell line.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4063
• Target Species: Human
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1