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Invitrogen™ CD229 Monoclonal Antibody (HLy9.25)
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Catalog No. PIMA544068
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100 μg
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PIMA544068 100 μg
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Catalog No. PIMA544068 Supplier Invitrogen™ Supplier No. MA544068
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Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells. Positive control: peripheral blood lymphocytes. Functional application: Regulation of activation.

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD229
Applications Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone HLy9.25
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Ly9
Gene Accession No. Q9HBG7
Gene Alias AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9
Gene Symbols Ly9
Host Species Mouse
Immunogen CD299-transfected 300.19 pre-B cell line.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4063
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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