Invitrogen™ CD231 Monoclonal Antibody (B2D), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA538697

Catalog No. PIMA538697

Description

This antibody recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.

TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

Specifications

• Antigen: CD231
• Classification: Monoclonal
• Concentration: 35 μg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: P41732
• Gene Symbols: TSPAN7
• Immunogen: Human T-ALL cell line THP-6.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: B2D
• Conjugate: APC
• Gene: TSPAN7
• Gene Alias: 1200014P11Rik; A15; AI323365; CCG-B7; CD231; CD231 antigen; cell surface glycoprotein A15; DXS1692E; membrane component chromosome X surface marker 1; membrane component, X chromosome, surface marker 1; MRX58; Mxs1; neuroprotective protein 5; PE31; R74651; TALLA; TALLA homolog; TALLA-1; T-cell acute lymphoblastic leukemia associated antigen 1; T-cell acute lymphoblastic leukemia-associated antigen 1; tetraspanin 7; tetraspanin protein; tetraspanin-7; TM4SF2; TM4SF2b; transmembrane 4 superfamily 2b; transmembrane 4 superfamily member 2; Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15); transmembrane protein A15; TSPAN7; tspan-7
• Host Species: Mouse
• Purification Method: Size-exclusion Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7102
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov