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Invitrogen™ CD24 Monoclonal Antibody (30-F1), APC
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Catalog No. 501137641
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25 μg
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Catalog No. Quantity
50-113-7641 25 μg
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Catalog No. 50-113-7641 Supplier Invitrogen™ Supplier No. A14745
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Description

Rat Monoclonal Antibody

CD24 Monoclonal Antibody for Flow

CD24 is a 35-50 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on a variety of cell types, including erythrocytes, thymocytes, peripheral lymphocytes, and cells of the myeloid lineage. It is variably glycosylated, resulting in heterogeneity in molecular mass across different cell lineages, which can affect antibody staining levels on lymphocyte populations. In the context of B-cell development, CD24 is expressed from the pro-B-cell stage in the bone marrow through to mature, surface Ig-positive B cells, with very low or negative expression on plasma cells. It is also present on the majority of B-lineage acute lymphoblastic leukemias, B-cell chronic lymphocytic leukemias (CCLs), and B-cell non-Hodgkin's lymphomas. CD24 is thought to play a role in regulating B-cell proliferation and maturation, as well as in controlling autoimmunity. Additionally, CD24 has been reported to interact with P-selectin (CD62P), indicating a potential role in cell adhesion and signaling. CD24 is a valuable marker for studying B-cell development, leukemia, lymphoma, and autoimmune regulation, as well as its interactions with other molecules like P-selectin.
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Specifications

Antigen CD24
Applications Flow Cytometry
Classification Monoclonal
Clone 30-F1
Concentration 0.1 mg/mL
Conjugate APC
Formulation PBS with <0.1% sodium azide; pH 7.5
Gene Cd24a
Gene Accession No. P24807
Gene Alias CD24; CD24 antigen; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 molecule; CD24A; CD24a antigen; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; heat-stable antigen; HSA; Ly-52; Lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; Nectadrin; nectadrin heat stable antigen; R13-Ag; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; X62 heat stable antigen
Gene Symbols Cd24a
Host Species Rat
Immunogen Mouse thymocytes or splenocytes.
Purification Method Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12484
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2c κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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