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CD249 Mouse, anti-Human, R718, Clone: 2D3/APA, BD OptiBuild™

Catalog No. BDB752260 Shop All BD Biosciences Products
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BDB752260 50 μg
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Catalog No. BDB752260 Supplier BD Biosciences Supplier No. 752260
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Description

Mouse Monoclonal Antibody

The 2D3 monoclonal antibody specifically binds to CD249. CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160. CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys. It is also expressed by early B-lineage cells and cell lines. CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides. This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure. It may also play roles in the regulation of angiogenesis and development of B cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD249
Applications Flow Cytometry
Classification Monoclonal
Clone 2D3/APA
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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