CD25/IL-2R alpha Antibody (Basiliximab), PE - Chimeric, Novus Biologicals™

Human Monoclonal Antibody

Supplier:  Novus Biologicals NBP275902PE

Catalog No. NBP275902PE

Description

CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Product Image.

Specifications

• Antigen: CD25/IL-2R alpha
• Classification: Monoclonal
• Conjugate: PE
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: IL2RA
• Immunogen: Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry
• Clone: Basiliximab
• Dilution: Flow Cytometry
• Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
• Host Species: Human
• Purification Method: Protein A purified
• Research Discipline: Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
• Gene ID (Entrez): 3559.0
• Target Species: Human, Cynomolgus Monkey, Rhesus Macaque
• Isotype: IgG1 κ