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Invitrogen™ CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), FITC
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Catalog No. PIMA110163
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100 μg
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Catalog No. Quantity
PIMA110163 100 μg
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Catalog No. PIMA110163 Supplier Invitrogen™ Supplier No. MA110163
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Description

Mouse Monoclonal Antibody

This antibody reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
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Specifications

Antigen CD264 (TRAIL-R4)
Applications Flow Cytometry
Classification Monoclonal
Clone TRAIL-R4-01
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene TNFRSF10D
Gene Accession No. Q9UBN6
Gene Alias CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Gene Symbols TNFRSF10D
Host Species Mouse
Immunogen TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8793
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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