Invitrogen™ CD264 (TRAIL-R4) Recombinant Rabbit Monoclonal Antibody (10Y1N4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542826

Catalog No. PIMA542826

Description

Positive test controls include: Mouse liver, Mouse kidney, Rat liver, Rat kidney. Immunogen sequence: PTQVSEQEIQ GQELAELTGV TVELPEEPQR LLEQAEAEGC QRRRLLVPVN DADSADISTL LDASATLEEG HAKETIQDQL VGSEKLFYEE DEAGSATSCL.

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.

Specifications

• Antigen: CD264 (TRAIL-R4)
• Classification: Recombinant Monoclonal
• Concentration: 0.61 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UBN6
• Gene Symbols: TNFRSF10D
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 287-386 of human DCR2 (Q9UBN6).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 10Y1N4
• Conjugate: Unconjugated
• Gene: TNFRSF10D
• Gene Alias: CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8793
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov