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Invitrogen™ CD266 (TWEAK Receptor) Polyclonal Antibody
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Catalog No. PIPA5109244
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100 μL
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PIPA5109244 100 μL
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Catalog No. PIPA5109244 Supplier Invitrogen™ Supplier No. PA5109244
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Rabbit Polyclonal Antibody

Positive Control: MCF-7, SiHa, human colon cancer tissue, human placenta tissue, mouse testis tissue, 293T.

TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by binding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD266 (TWEAK Receptor)
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene TNFRSF12A
Gene Accession No. Q9NP84
Gene Alias AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Gene Symbols TNFRSF12A
Host Species Rabbit
Immunogen Synthetic peptide within Human TWEAKR aa 80-129.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51330
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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