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  6. CD27/TNFRSF7 Mouse anti-Human, Clone: 203.6, Novus Biologicals™

CD27/TNFRSF7 Mouse anti-Human, Clone: 203.6, Novus Biologicals™
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Catalog No. NBP247914B Shop All R&D Systems Products
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0.2 mg
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NBP247914B 0.2 mg
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Catalog No. NBP247914B Supplier Novus Biologicals Supplier No. NBP2479140.2MG

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

CD27/TNFRSF7 Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen CD27/TNFRSF7
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone 203.6
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CD27 antigen, CD27 molecule, MGC20393, S152CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T14, TNFRSF7T-cell activation antigen CD27, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7
Gene Symbols CD27
Host Species Mouse
Immunogen Sezary cells
Molecular Weight of Antigen 120 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Apoptosis, B Cell Development and Differentiation Markers, Cancer, Immunology, Innate Immunity
Primary or Secondary Primary
Gene ID (Entrez) 939
Test Specificity Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG3 κ
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