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CD271 (NGF Receptor) Monoclonal Antibody (ME20.4), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

$145.00 - $1562.00

Specifications

Antigen CD271 (NGF Receptor)
Clone ME20.4
Concentration 0.5 mg/mL
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-255-0880
Encompass_Preferred
View Documents
Invitrogen™
14940080
25 μg
Each for $145.00
Only null left
Add to Cart
 
14-940-037
Encompass_Preferred
View Documents
Invitrogen™
14940037
2 mg
Each for $1,562.00
Only null left
Add to Cart
 
Description

Description

The MAb ME20.4 recognizes CD271, a 75 kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9. The ME20.4 MAb recognizes human, Non-human Primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
Specifications

Specifications

CD271 (NGF Receptor)
0.5 mg/mL
Unconjugated
Mouse
Human, Mouse, Rat, Canine, Rabbit, Monkey, Sheep, Pig
P07174, P08138, Q9Z0W1
IgG1 κ
Affinity chromatography
Antibody
ME20.4
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
100349095, 100525607, 101119064, 18053, 24596, 4804, 491071
Primary
4°C
Ngfr
Videos
SDS
Documents

Documents

Product Certifications
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