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  6. Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™ 

Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™
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Catalog No. 366598282
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36-659-8282 100 μg
36-659-8280 25 μg
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Catalog No. 36-659-8282 Supplier Invitrogen™ Supplier No. 366598282
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Description

Rat Monoclonal Antibody

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
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Specifications

Antigen CD274 (PD-L1, B7-H1)
Applications Flow Cytometry
Classification Monoclonal
Clone MIH5
Concentration 0.2 mg/mL
Conjugate Brilliant Ultraviolet 615
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Cd274
Gene Accession No. Q9EP73
Gene Alias A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols Cd274
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60533
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a λ
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