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  6. Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), NovaFluor™ Red 755, eBioscience™, Invitrogen™ 

Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), NovaFluor™ Red 755, eBioscience™, Invitrogen™

Catalog No. M036T03R06A
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M036T03R06A 100 μg
M036T02R06A 25 μg
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Catalog No. M036T03R06A Supplier Invitrogen™ Supplier No. M036T03R06A
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Description

Rat Monoclonal Antibody

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD274 (PD-L1, B7-H1)
Applications Flow Cytometry
Classification Monoclonal
Clone MIH5
Concentration 0.1 mg/mL
Conjugate NovaFluor Red 755
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Cd274
Gene Accession No. Q9EP73
Gene Alias A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols Cd274
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60533
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG2a λ
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