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Invitrogen™ CD275 (B7-H2) Recombinant Rat Monoclonal Antibody (HK5.3)
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Catalog No. PIMA548099
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200 μg
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Catalog No. Quantity
PIMA548099 200 μg
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Catalog No. PIMA548099 Supplier Invitrogen™ Supplier No. MA548099
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Description

Rat Recombinant Monoclonal Antibody

Specificity: This antibody specifically binds to mouse ICOSL and competes with binding of ICOS.

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD275 (B7-H2)
Applications Flow Cytometry, Inhibition Assays
Classification Recombinant Monoclonal
Clone HK5.3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Icosl
Gene Accession No. Q9JHJ8
Gene Alias AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand
Gene Symbols Icosl
Host Species Rat
Immunogen This antibody was raised by immunizing SD rat with mouse B7h-transfected L cells and fusing immune splenocytes with P3U1 myeloma cells and screened for binding to mouse B7h-transfected NRK cells.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50723
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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