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Description
The MIH32 monoclonal antibody specifically binds to CD276, also known as B7-H3 (B7 homolog 3). CD276 is a type I transmembrane glycoprotein and member of the B7-family of regulatory proteins. The expression of B7-H3 can be induced on T cells, natural killer (NK) cells and antigen presenting cells. B7-H3 is up-regulated during the differentiation of monocytes into dendritic cells or during the interaction between dendritic cells and regulatory T cells. In addition, B7-H3 is found to be expressed on fibroblasts, fibroblast-like synoviocytes and epithelial cells. CD276 (B7-H3) can function as a positive or a negative regulator of T responses.
Specifications
Specifications
| Antigen | CD276 (B7-H3) |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MIH32 |
| Conjugate | R718 |
| Host Species | Mouse |
| Quantity | 50 μg |
| Regulatory Status | RUO |
| Primary or Secondary | Primary |
| Target Species | Mouse |
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