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CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Brilliant Violet™ 650, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$194.00 - $398.00
Specifications
| Antigen | CD279 (PD-1) |
|---|---|
| Clone | eBioJ105 (J105) |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
41-627-9942
|
Invitrogen™
416279942 |
100 Tests |
Each for $398.00
|
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41-627-9941
|
Invitrogen™
416279941 |
25 Tests |
Each for $194.00
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Description
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "e;danger signals"e; such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.Specifications
| CD279 (PD-1) | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2 | |
| Pdcd1 | |
| Primary | |
| 4°C, store in dark, DO NOT FREEZE! |
| eBioJ105 (J105) | |
| Flow Cytometry | |
| Brilliant Violet 650 | |
| Mouse | |
| Human, Rhesus Macaque | |
| Q15116 | |
| 100135775, 5133 | |
| IgG1 κ | |
| Affinity chromatography | |
| Pdcd1 |
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