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CD279 (PD-1) Mouse anti-Human, Clone: MIH4, eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 14996937

Encompass

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Catalog No. 14-996-937


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Description

Description

The MIH4 MAb reacts with the human PD-1 (programmed death-1), a 55 kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.

CD279 (PD-1) Monoclonal antibody specifically detects CD279 (PD-1) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen)
Specifications

Specifications

CD279 (PD-1)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q15116
Mouse
2 mg
Primary
Human
Liquid
Flow Cytometry, Immunohistochemistry (Frozen)
MIH4
Unconjugated
Pdcd1
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; Protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Affinity chromatography
RUO
5133
Antibody
IgG1 κ
Safety and Handling

Safety and Handling

SDS
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Product Certifications
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