CD28 Antibody (CB28), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP232928F	Novus Biologicals NBP2329280.02MG	0.02 mg
NBP232928A	Novus Biologicals NBP2329280.1MG	0.1 mg
NBP232928B	Novus Biologicals NBP2329280.2MG	0.2 mg

Description

CD28 Monoclonal specifically detects CD28 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional.

Specifications

• Antigen: CD28
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P10747
• Gene ID (Entrez): 940
• Immunogen: Recombinant human CD28 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: CB28
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Adaptive Immunity, Apoptosis, Immunology
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44
• Gene Symbols: CD28
• Isotype: IgG1 κ
• Purification Method: Protein A purified
• Test Specificity: Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.