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CD29 Mouse anti-Human, Brilliant Violet 650, Clone: MAR4., BD Optibuild™

Catalog No. BDB743785 Shop All BD Biosciences Products
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BDB743785 50 μg
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Catalog No. BDB743785 Supplier BD Biosciences Supplier No. 743785
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Description

Mouse Monoclonal Antibody

The MAR4 monoclonal antibody specifically binds to CD29. CD29 is a 130 kDa integrin 1 subunit that is expressed as a heterodimeric complex with one of six distinct subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. The 1 subunit has a broad tissue distribution; it is expressed on lymphocytes, monocytes and weakly on granulocytes, but not on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination. BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm. Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD29
Classification Monoclonal
Clone MAR4.
Concentration 0.2mg/mL
Conjugate Brilliant Violet 650
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias ITGB1, Integrin beta-1, Integrin β1, FNRB, GPIIA, ITB1, MDF2, MSK12, VLA-4β
Host Species Mouse
Immunogen Purified Human α5β1 Fibronectin Receptor
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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