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Invitrogen™ CD299 (DC-SIGN/L) Monoclonal Antibody (2G1)
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Catalog No. PIMA521012
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100 μg
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Catalog No. Quantity
PIMA521012 100 μg
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Catalog No. PIMA521012 Supplier Invitrogen™ Supplier No. MA521012
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Description

Mouse Monoclonal Antibody

Peptide Sequence: SQRNWHDSVT ACQEVRAQLV VIKTAEEQNF LQLQTSRSNR FSWMGLSDLN QEGTWQWVDG SPLSPSFQRY WNSGEPNNSG NEDCAEFSGS GWNDNRCDVD NYWICKKPAA.

CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
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Specifications

Antigen CD299 (DC-SIGN/L)
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2G1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene CLEC4M
Gene Accession No. Q9H2X3
Gene Alias CD209 antigen-like protein 1; Cd209b; CD209b antigen; CD209L; CD209L1; CD299; CD299 antigen; CLEC4M; C-type lectin domain family 4 member M; C-type lectin domain family 4, member M; DC-SIGN2; DCSIGNR; DC-SIGNR; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; LSIGN; L-SIGN; mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866
Gene Symbols CLEC4M
Host Species Mouse
Immunogen CLEC4M (NP_055072, 285 a.a. ~ 394 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10332
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG3 λ
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