Invitrogen™ CD299 (DC-SIGN/L) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113323

Catalog No. PIPA5113323

Description

CD299 (DC-SIGN/L) Polyclonal Antibody for Western Blot, ICC/IF, ELISA

CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Specifications

• Antigen: CD299 (DC-SIGN/L)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLEC4M
• Gene Alias: CD209 antigen-like protein 1; Cd209b; CD209b antigen; CD209L; CD209L1; CD299; CD299 antigen; CLEC4M; C-type lectin domain family 4 member M; C-type lectin domain family 4, member M; DC-SIGN2; DCSIGNR; DC-SIGNR; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; LSIGN; L-SIGN; mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10332
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 3.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9H2X3
• Gene Symbols: CLEC4M
• Immunogen: Recombinant Human C-type lectin domain family 4 member M protein (238-382AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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