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Invitrogen™ CD299 (DC-SIGN/L) Polyclonal Antibody
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Catalog No. PIPA542164
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100 μL
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PIPA542164 100 μL
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Catalog No. PIPA542164 Supplier Invitrogen™ Supplier No. PA542164
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Description

Rabbit Polyclonal Antibody

Peptide sequence: LVLQLLSFML LAGVLVAILV QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV Sequence homology: Human: 100%; Pig: 86%.

CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
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Specifications

Antigen CD299 (DC-SIGN/L)
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CLEC4M
Gene Accession No. Q9H2X3
Gene Alias CD209 antigen-like protein 1; Cd209b; CD209b antigen; CD209L; CD209L1; CD299; CD299 antigen; CLEC4M; C-type lectin domain family 4 member M; C-type lectin domain family 4, member M; DC-SIGN2; DCSIGNR; DC-SIGNR; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; LSIGN; L-SIGN; mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866
Gene Symbols CLEC4M
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human CLEC4M (aa 51-100).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10332
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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