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Invitrogen™ CD2AP Monoclonal Antibody (5F8)
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Catalog No. PIMA533009
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Quantity:
100 μg
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Catalog No. Quantity
PIMA533009 100 μg
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Catalog No. PIMA533009 missing translation for 'mfr' Invitrogen™ missing translation for 'supplierNo' MA533009
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Description

Mouse Monoclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human K562 whole cell, human A431 whole cell, human HEK293 whole cell, human U20S whole cell, human HL-60 whole cell, human MCF-7 whole cell, human Hela whole cell, human PANC-1 whole cell, rat liver tissue, rat testicular tissue, mouse pancreas tissue, mouse testicular tissue, mouse RAW2467 whole cell. IHC: human mammary cancer, human mammary cancer, human colon cancer, human placenta tissue, mouse kidney tissue, rat brain tissue. ICC/IF: A431 cell. Flow: K562 cell, U20S cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2AP
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5F8
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene CD2AP
Gene Accession No. F1LRS8, Q9JLQ0, Q9Y5K6
Gene Alias adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; CD2 associated protein; Cd2ap; CD2-associated protein; CMS; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets1; METS-1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Gene Symbols CD2AP
Host Species Mouse
Immunogen E.coli-derived human CD2AP recombinant protein (Position: K253-K337).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12488, 23607, 316258
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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