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Invitrogen™ CD2AP Polyclonal Antibody
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Catalog No. PIPA596807
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100 μL
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PIPA596807 100 μL
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Catalog No. PIPA596807 Supplier Invitrogen™ Supplier No. PA596807
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Description

Rabbit Polyclonal Antibody

Positive Samples: A-431, Raji, MCF7, SW480, HL-60, Mouse kidney, Rat kidney; Cellular Location: Cell projection, Cytoplasm, cytoskeleton, ruffle Immunogen sequence: KYFSLKPEEK DEKSTLEQKP SKPAAPQVPP KKPTPPTKAS NLLRSSGTVY PKRPEKPVPP PPPIAKINGE VSSISSKFET EPVSKLKLDS EQLPLRPKSV DFDSLTVRTS KETDVVNFDD IASSENLLHL TANRPKMPGR RLPGRFNGGH SPTHSPEKIL KLPKEEDSAN LKPSELKKDT CYSPKPSVYL STPSSASKAN TTAFLTPLEI KAKVETDDVK KNSLDELRAQ IIELLCIVEA LKKDHGKELE KLRKDLEEEK TMRSNLEMEI EKLKKAVLSS.

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2AP
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CD2AP
Gene Accession No. F1LRS8, Q9JLQ0, Q9Y5K6
Gene Alias adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; CD2 associated protein; Cd2ap; CD2-associated protein; CMS; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets1; METS-1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Gene Symbols CD2AP
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 360-639 of human CD2AP (NP_0362521).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12488, 23607, 316258
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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