Cd2ap Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5869	Proteintech Group Inc 510461AP150UL	150 μL

Description

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Specifications

• Antigen: Cd2ap
• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q9JLQ0, Q9Y5K6
• Gene ID (Entrez): 12488, 23607
• Immunogen: Cd2ap Fusion Protein Ag0622
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CD2AP

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: AL024079, C78928, CD2 associated protein, Cd2ap, METS 1
• Gene Symbols: CD2AP
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody