CD3/CD20 Antibody Cocktail, Invitrogen™

Catalog No.	Quantity
PIMA514433	7 mL

Catalog No. PIMA514433 Supplier Thermo Scientific Supplier No. MA514433

Description

Antibody Cocktail

MA5-14433 targets CD3/CD20 in IHC (P) and WB applications and shows reactivity with Human, Mouse and Rat samples. CD3 (clone SP7) is a rabbit monoclonal IgG antibody. CD20 (clone L26) is an IgG2a mouse monoclonal antibody. The MA5-14433 immunogen is synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protein; the CD20 immunogen is human tonsil B cells.

The CD3 antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by normal and neoplastic T-lymphocytes. It stains human T-lymphocytes in both cortex and medulla of the thymus and in peripheral lymphoid tissues. CD20 is a non-Ig differentiation antigen of B-lymphocytes and the expression of CD20 is restricted to normal and neoplastic B-lymphocytes, being absent from all other leukocytes and tissues. The CD3-CD20 cocktail reveals lymphoid architecture in neoplastic situations.

Specifications

• Antigen: CD3/CD20
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Cocktail
• Clone: CD3-SP7; CD20-L26
• Conjugate: Unconjugated
• Formulation: tris HCl with proprietary stabilizer and <0.1% sodium azide; pH 7.6
• Gene: MS4A1
• Gene Accession No.: P04234, P04235, P07766, P09693, P11836, P11942, P19377, P19437, P22646, Q64159
• Gene Alias: AA960661; AI504783; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CD3; CD3 antigen delta polypeptide; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 delta; CD3 gamma-chain; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; Cd3d; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Ctg3; Ctg-3; CVID5; IMD17; IMD18; IMD19; LEU-16; Leukocyte surface antigen Leu-16; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; Ms4a1; Ms4a2; OKT3, delta chain; S7; T3d; T3e; T3G; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; TCRE
• Gene Symbols: CD3D, Cd3e, CD3G, MS4A1
• Host Species: Mixed, Rabbit
• Immunogen: synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protien; CD20- Human tonsil B cells
• Purification Method: purified
• Quantity: 7 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12482, 12500, 12501, 12502, 25710, 300678, 309217, 315609, 915, 916, 917, 931
• Target Species: Human, Mouse, Rat
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ