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Invitrogen™ CD3d Polyclonal Antibody
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Catalog No. PIPA5102404
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100 μL
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PIPA5102404 100 μL
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Catalog No. PIPA5102404 Supplier Invitrogen™ Supplier No. PA5102404
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CD3D.

CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3d
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cd3d
Gene Accession No. P04234, P04235, P19377
Gene Alias CD3 antigen delta polypeptide; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 delta; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3D; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; IMD19; OKT3, delta chain; T3D; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain
Gene Symbols Cd3d
Host Species Rabbit
Immunogen A synthesized peptide derived from human CD3D(Accession P04234), corresponding to amino acid residues I108-A158.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12500, 25710, 915
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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