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CD3 epsilon Antibody (C3e/1931), FITC, Novus Biologicals™
SDP

Catalog No. NB010827 Shop All R&D Systems Products
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NB010827 0.1 mL
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Catalog No. NB010827 Supplier Novus Biologicals Supplier No. NBP279840F
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Description

Mouse Monoclonal Antibody

CD3 epsilon Monoclonal specifically detects CD3 epsilon in Human samples. It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CD3 epsilon
Applications Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone C3e/1931
Conjugate FITC
Dilution Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
Gene Symbols CD3E
Host Species Mouse
Immunogen A recombinant human CD3 epsilon protein fragment (around aa 23-119) (exact sequence is proprietary) (Uniprot: P07766)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Primary or Secondary Primary
Test Specificity Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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