CD3 epsilon Antibody (PC3/188A), PE/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254405PECY7

Catalog No. N254405PEC7

Description

CD3 epsilon Monoclonal specifically detects CD3 epsilon in Human, Rat, Porcine, Bovine, Chicken, Equine, Guinea Pig, Rabbit samples. It is validated for Flow Cytometry.

Specifications

• Antigen: CD3 epsilon
• Classification: Monoclonal
• Conjugate: PE-Cyanine7
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CD3E
• Immunogen: A synthetic peptide corresponding to amino acids 156-168 of the cytoplasmic domain of human CD3- chain (Uniprot: P07766 )
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: PC3/188A
• Dilution: Flow Cytometry
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
• Gene ID (Entrez): 916.0
• Target Species: Human, Rat, Pig, Bovine, Chicken, Equine, Rabbit
• Isotype: IgG1