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CD3 Molecular Complex Rat anti-Mouse, FITC, Clone: 17A2, BD

Catalog No. BDB561798 Shop All BD Biosciences Products
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BDB561798 0.1 mg
BDB555274 0.5 mg
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Description

Rat Monoclonal Antibody

The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes. Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells. The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11. This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3 Molecular Complex
Applications Flow Cytometry
Classification Monoclonal
Clone 17A2
Concentration 0.5mg/mL
Conjugate FITC
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Rat
Immunogen γδ TCR-positive T-T hybridoma D1
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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