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CD3 Mouse anti-Human, FITC, Clone: Hit3a, Abnova™

Catalog No. 89933772 Shop All Abnova Corporation Products
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89-933-772 100 Reactions
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Catalog No. 89-933-772 Supplier Abnova Corporation Supplier No. MAB12202
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Description

Mouse monoclonal antibody raised against CD3.

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq]

Specifications

Antigen CD3
Applications Flow Cytometry
Classification Monoclonal
Clone Hit3a
Conjugate FITC
Description Mouse monoclonal antibody raised against CD3.
Dilution Flow Cytometry The optimal working dilution should be determined by the end user.
Formulation In PBS, pH7.2 (0.09% Sodium azide, may contain carrier protein/stabilizer).
Gene Alias FLJ18683/T3E/TCRE
Gene Symbols CD3E
Host Species Mouse
Immunogen CD3
Purification Method Affinity Chromatography
Quantity 100 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 916
Test Specificity The clone HIT3a monoclonal antibody reacts with human CD3e.
Target Species Human
Content And Storage Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Form Liquid
Isotype IgG2a κ
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