CD30 (Reed-Sternberg Cell Marker) Ab-4 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD30 (Reed-Sternberg Cell Marker) Ab-4, Mouse Monoclonal Antibody.

Supplier:  Epredia MS1857P0

Catalog No. MS1857P0

Description

CD30, a single chain glycoprotein, is synthesized as a 90 kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin's disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Host Species: Mouse

Clone: HRS4

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Recombinant extracellular domain of CD30 protein

Molecular Weight: 120 kDa (mature), 95 kDa (precursor)

Positive Control: Hodgkin's lymphoma

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: CD30 Ab-4
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Oncogenesis
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: HRS4
• Conjugate: Unconjugated
• Immunogen: Recombinant extracellular domain of CD30 protein
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated