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Invitrogen™ CD300b Polyclonal Antibody
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Catalog No. PIPA599853
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100 μL
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PIPA599853 100 μL
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Catalog No. PIPA599853 Supplier Invitrogen™ Supplier No. PA599853
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CD300LB.

CD300 molecule-like family member b (CD300LB), also known as CLM-7, is a gene located on chromosome 17q25.1, encoding an immunoreceptor that belongs to the CD300 family of molecules. CD300LB is primarily expressed on the surface of myeloid cells, including dendritic cells and macrophages, where it plays an essential role in modulating immune responses. The receptor is involved in the regulation of cell activation and inflammatory responses through its interactions with phosphatidylserine and other lipid ligands, which can lead to either activation or inhibition of immune cell functions. CD300LB influences processes like antigen presentation, phagocytosis, and cytokine production, thereby impacting innate immune responses and the maintenance of immune homeostasis. Its expression and activity are of particular interest in contexts like autoimmunity, infection, and cancer, where it may contribute to disease progression and serve as a potential therapeutic target in modulating immune functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD300b
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CD300LB
Gene Accession No. A8K4G0
Gene Alias CD300 antigen like family member B; CD300 antigen-like family member B; CD300 molecule like family member b; CD300 molecule-like family member b; CD300b; CD300LB; CLM7; CLM-7; CMRF35A2; CMRF35-A2; CMRF35-like molecule 7; CMRF-35-like molecule-7; Gm253; Immune receptor expressed on myeloid cells 3; IREM3; IREM-3; Leukocyte mono-Ig-like receptor 5; LMIR5; TREM5; TREM-5; triggering receptor expressed on myeloid cells 5; UNQ2530/PRO6029
Gene Symbols CD300LB
Host Species Rabbit
Immunogen A synthesized peptide derived from human CD300LB(Accession A8K4G0), corresponding to amino acid residues V155-T201.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124599
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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