Invitrogen™ CD300e Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553324

Catalog No. PIPA553324

Description

Immunogen sequence: TVWCQYESMY KGYNKYWCRG QYDTSCESIV ETKGEEKVER NGRVSIRDHP EALAFTVTMQ NLNEDDAGSY WCKIQTVWVL DSWSRDPSDL VRVYVSPAIT TPRRTTHPAT PPIFLVVNPG RNLSTGEVLT QNSGFR Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.

CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is down regulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.

Specifications

• Antigen: CD300e
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CD300E
• Gene Alias: BC034097; CD300 antigen like family member E; CD300 antigen-like family member E; CD300e; CD300e antigen; CD300e molecule; Cd300le; CLM2; CLM-2; CMRF35A5; CMRF35-A5; CMRF35-like molecule 2; CMRF-35-like molecule-1; Immune receptor expressed on myeloid cells 2; IREM2; IREM-2; PIgR2; PIgR-2; poly-Ig receptor 2; polymeric immunoglobulin receptor 2; TREM5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 342510
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q496F6
• Gene Symbols: CD300E
• Immunogen: Recombinant protein corresponding to Human CD300e. Recombinant protein control fragment (Product #RP-90569).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov