Invitrogen™ CD300g Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106823

Catalog No. PIPA5106823

Description

Antibody detects endogenous levels of total CD300LG.

CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.

Specifications

• Antigen: CD300g
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CD300LG
• Gene Alias: 2310016B05Rik; CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule like family member g; Cd300 molecule-like family member G; CD300g; CD300g antigen; Cd300lg; Clm9; CLM-9; CLM9Trem4; CMRF35-like molecule 9; CMRF-35-like molecule-9; D11Ertd736e; Nepmucin; RGD1311074; TREM4; TREM-4; Triggering receptor expressed on myeloid cells 4; UNQ422/PRO846
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 146894, 52685
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q1ERP8, Q6UXG3
• Gene Symbols: CD300LG
• Immunogen: A synthesized peptide derived from human CD300LG(Accession Q6UXG3), corresponding to amino acid residues A168-M218.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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