Invitrogen™ CD300g Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580429

Catalog No. PIPA580429

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CLM-9/TREM4.

CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.

Specifications

• Antigen: CD300g
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CD300LG
• Gene Alias: 2310016B05Rik; CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule like family member g; Cd300 molecule-like family member G; CD300g; CD300g antigen; Cd300lg; Clm9; CLM-9; CLM9Trem4; CMRF35-like molecule 9; CMRF-35-like molecule-9; D11Ertd736e; Nepmucin; RGD1311074; TREM4; TREM-4; Triggering receptor expressed on myeloid cells 4; UNQ422/PRO846
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 146894
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 5 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q6UXG3
• Gene Symbols: CD300LG
• Immunogen: Recombinant Human CLM-9/TREM4 protein (Met1-Arg247).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG