Invitrogen™ CD300g Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547755

Catalog No. PIPA547755

Description

In direct ELISAs, less than 1% cross-reactivity with recombinant human CD300g/Nepmucin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.

Specifications

• Antigen: CD300g
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CD300LG
• Gene Alias: 2310016B05Rik; CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule like family member g; Cd300 molecule-like family member G; CD300g; CD300g antigen; Cd300lg; Clm9; CLM-9; CLM9Trem4; CMRF35-like molecule 9; CMRF-35-like molecule-9; D11Ertd736e; Nepmucin; RGD1311074; TREM4; TREM-4; Triggering receptor expressed on myeloid cells 4; UNQ422/PRO846
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 52685
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q1ERP8
• Gene Symbols: CD300LG
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CD300g/Nepmucin Leu19-Ile284.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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