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Invitrogen™ CD300g Polyclonal Antibody
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Catalog No. PIPA547755
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100 μg
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PIPA547755 100 μg
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Catalog No. PIPA547755 Supplier Invitrogen™ Supplier No. PA547755
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 1% cross-reactivity with recombinant human CD300g/Nepmucin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD300g
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CD300LG
Gene Accession No. Q1ERP8
Gene Alias 2310016B05Rik; CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule like family member g; Cd300 molecule-like family member G; CD300g; CD300g antigen; Cd300lg; Clm9; CLM-9; CLM9Trem4; CMRF35-like molecule 9; CMRF-35-like molecule-9; D11Ertd736e; Nepmucin; RGD1311074; TREM4; TREM-4; Triggering receptor expressed on myeloid cells 4; UNQ422/PRO846
Gene Symbols CD300LG
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse CD300g/Nepmucin Leu19-Ile284.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52685
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

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