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Invitrogen™ CD300g Recombinant Rabbit Monoclonal Antibody (102)
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Catalog No. PIMA530254
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PIMA530254 100 μL
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Catalog No. PIMA530254 Supplier Invitrogen™ Supplier No. MA530254
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Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human CLM-9/TREM4.

CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD300g
Applications ELISA
Classification Recombinant Monoclonal
Clone 102
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CD300LG
Gene Accession No. Q6UXG3
Gene Alias 2310016B05Rik; CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule like family member g; Cd300 molecule-like family member G; CD300g; CD300g antigen; Cd300lg; Clm9; CLM-9; CLM9Trem4; CMRF35-like molecule 9; CMRF-35-like molecule-9; D11Ertd736e; Nepmucin; RGD1311074; TREM4; TREM-4; Triggering receptor expressed on myeloid cells 4; UNQ422/PRO846
Gene Symbols CD300LG
Host Species Rabbit
Immunogen Recombinant Human CLM-9/TREM4 Protein (Met1-Arg247).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 146894
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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