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Invitrogen™ CD31 Monoclonal Antibody (LCI-9)
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Catalog No. PIMA182381
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2 mL
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PIMA182381 2 mL
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Catalog No. PIMA182381 Supplier Invitrogen™ Supplier No. MA182381
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Description

Mouse Monoclonal Antibody

Mouse anti Pig CD31 antibody, clone LCI-9 recognizes porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1.

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
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Specifications

Antigen CD31
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone LCI-9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.09% sodium azide
Gene Pecam1
Gene Accession No. Q95242
Gene Alias C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gene Symbols Pecam1
Host Species Mouse
Immunogen Porcine CD31/human IgGFc fusion protein.
Quantity 2 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 396941
Target Species Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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Safety and Handling

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