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CD31 Mouse, anti-Human, R718, Clone: M89D3, BD OptiBuild™

Catalog No. BDB752186 Shop All BD Biosciences Products
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BDB752186 50 μg
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Catalog No. BDB752186 Supplier BD Biosciences Supplier No. 752186
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Description

Mouse Monoclonal Antibody

The M89D3 monoclonal antibody specifically recognizes CD31, which is also known as platelet endothelial cell adhesion molecule -1 (PECAM-1), a single chain, type I transmembrane protein of approximately 130-140 kDa. CD31 is a member of the immunoglobulin supergene family. Its extracellular region is composed of 574 amino acids and contains six C2-type Ig domains, and the intracellular region is composed of 118 residues. CD31 (PECAM-1) is expressed on endothelial cells, platelets, monocytes, neutrophils and NK cells. It has also been observed on subsets of T cells, but not on circulating B cells. It has been implicated in a number of cellular phenomena, including vascular wound healing, angiogenesis, and transendothelial migration of leukocytes and platelet aggregation in inflammatory responses.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD31
Applications Flow Cytometry
Classification Monoclonal
Clone M89D3
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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