Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD31 Rat anti-Mouse, PE, Clone: MEC 13.3, BD

Rat Monoclonal Antibody

$68.00 - $344.00

Specifications

Antigen CD31
Clone MEC 13.3
Concentration 0.2mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB561073
View Documents
BD Biosciences
561073
25 μg
Each for $68.00
Only null left
Add to Cart
 
BDB553373
View Documents
BD Biosciences
553373
0.2 mg
Each for $344.00
Only null left
Add to Cart
 
Description

Description

The MEC13.3 antibody reacts with CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1). CD31 is a 130 kDa integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion. CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is also expressed on many peripheral leukocytes and platelets. It has also been detected on bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 is involved in the transendothelial emigration of neutrophils, and neutrophil PECAM-1 appears to be down-regulated after extravasation into inflamed tissues. Multiple alternatively spliced isoforms are detected during early post-implantation embryonic development; this alternative splicing is involved in the regulation of ligand specificity. CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31. CD31-mediated endothelial cell-cell interactions are involved in angiogenesis. The MEC13.3 mAb inhibits a variety of in vitro and in vivo functions mediated by CD31.

Specifications

Specifications

CD31
0.2mg/mL
Monoclonal
Rat
Mouse
129/Sv mouse-derived endothelioma cell line tEnd.1
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
MEC 13.3
Flow Cytometry
PE
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
PECAM-1
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.